What advantage does combination therapy offer in hypertension management?

Combination therapy in hypertension management provides better blood pressure control through the synergistic effects of multiple medications. Different classes of antihypertensive drugs work via various mechanisms to lower blood pressure, targeting different pathways in the body. For instance, one medication might relax blood vessels while another reduces blood volume. When used together, these medications can enhance each other's effects, leading to a more significant reduction in blood pressure than what might be achieved with a single agent alone.

This approach is particularly beneficial for patients who do not achieve target blood pressure levels with monotherapy. Additionally, using lower doses of multiple medications can minimize side effects and improve patient adherence to the treatment regimen, further contributing to better overall management of hypertension.