What is a key patient education point for someone prescribed a statin for cholesterol management?

A crucial patient education point when prescribing a statin for cholesterol management is to avoid grapefruit products. Statins are metabolized by the liver, primarily through the cytochrome P450 enzyme system, specifically CYP3A4. Grapefruit juice has been shown to inhibit this enzyme, which can lead to increased levels of the statin in the blood. This elevation can increase the risk of side effects, including muscle pain and the potentially serious condition known as rhabdomyolysis. Therefore, advising patients to avoid grapefruit and its products helps ensure the safe and effective use of statins in managing cholesterol levels.