Which statement is correct regarding hydrochlorothiazide (HCTZ)?

Hydrochlorothiazide (HCTZ) is a thiazide diuretic commonly used to treat high blood pressure and fluid retention. One important aspect of taking HCTZ is the potential for orthostatic hypotension, which is a sudden drop in blood pressure that can occur when a person stands up or changes positions quickly. This can lead to dizziness, lightheadedness, or even fainting, particularly when starting the medication or after a dose increase. Therefore, it is essential for patients to take extra care when standing up or changing positions to avoid these adverse effects.

The majority of the other statements present inaccuracies regarding the medication. For example, diet can play a role in managing certain side effects of HCTZ, such as potassium levels, indicating that dietary considerations are important. Additionally, HCTZ does not exclusively affect the kidneys; it works by influencing sodium and water retention in the body and can also have effects on other systems, including blood pressure regulation. Monitoring blood pressure is crucial while on this medication to ensure that it is effectively controlling hypertension and to avoid potential complications that could arise from uncontrolled blood pressure levels.